منابع مشابه
COST-257 Final Report
Preface This synopsis outlines the results of the COST-257 project, prepared for the final seminar to take place in Würzburg, Germany from 27.– 29.9.2000. COST belongs to a framework programme initiated by the Euro-pean Union and stands for " Cooperation in the field of Scientific and Technical Research " of EU, Central and Eastern European countries as well as of institutions from non-COST mem...
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In recent years, many new designer drugs have emerged, including the group of cathinone derivatives. One frequently occurring drug is mephedrone; although mephedrone was originally considered as a “legal high” product, it is currently banned inmostWestern countries. Despite the banning, abuse of the drug and seizures are continuously reported. Although the metabolism of mephedrone has been stud...
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Dabigatran etexilate, an oral, reversible, competitive, and direct thrombin inhibitor, is an in vitro and in vivo substrate of Pglycoprotein (P-gp). Dabigatran etexilate was proposed as an in vivo probe substrate for intestinal P-gp inhibition in a recent guidance on drug-drug interactions (DDI) from the European Medicines Agency (EMA) and the Food and Drug Administration (FDA). We conducted tr...
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Fibroblast growth factor 21 (FGF21) is an atypical member of the FGF family that functions as an endocrine hormone. Pharmacologic studies show that FGF21 has broadmetabolic actions in obese rodents and primates that include enhancing insulin sensitivity, decreasing triglyceride concentrations, and causing weight loss. In lean rodents, FGF21 expression is strongly induced in liver by prolonged f...
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The neural crest is a stem/progenitor cell population that contributes to a wide variety of derivatives, including sensory and autonomic ganglia, cartilage and bone of the face and pigment cells of the skin. Unique to vertebrate embryos, it has served as an excellent model system for the study of cell behavior and identity owing to its multipotency, motility and ability to form a broad array of...
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ژورنال
عنوان ژورنال: Pediatric Critical Care Medicine
سال: 2018
ISSN: 1529-7535
DOI: 10.1097/01.pcc.0000537714.20893.85